30 patients (25 men, 05 women) over a period of six months with traumatic knee injury (no suspected fractures) were prospectively examined by high resolution musculoskeletal ultrasonography (Siemens Acuson X-300 with high frequency linear transducer probe- 7-12 MHz) and 0.2 Tesla MRI system within 4 weeks of injury by two independent examiners. Ultrasound examination was carried out in four quadrants – anterior, medial, lateral and posterior in the longitudinal and transverse direction.
Changes occurring in the plasma membrane, nuclear membrane, especially the intranuclear matrix are the primary cause of cancer. These changes can be triggered by various factors: exposure to chemicals, viruses, radiation, mechanical damage, etc. Changes in the ratio of the lipid composition of cells, a change in the sphingomyelin / cholesterol ratio of the nuclear membrane and the nuclear matrix leads to DNA mutations.